Ultra-Pure Guanidine Hydrochloride which CAS number is 50-01-1, its assay is above 99.5%. It is also can be customized according to customers’ requirements. We can produce it with superior quality and supply in time. We can send documents such as TDS,COA,MSDS to customers.
1. Product Introduction
Guanidine Hydrochloride Pharma Grade is the intermediate of medicine, pesticide and other organic compounds. It is an important raw material for the manufacture of sulfonamides and folic acid. We can produce Guanidine Hydrochloride with high quality and reasonable price and supply in time, Our customers from Europe, USA, India and we are expecting become your long-term partner in china.
2.Product Technical Parameter
Analysis Index |
Standard (QB/TZHG04-2016) |
Appearance |
White Crystal |
Assay % |
≥99.5% |
Ammonium Chloride % |
≤0.1% |
Water-insoluble % |
≤0.05% |
Loss on drying% |
≤0.3% |
Residue on ignition % |
≤0.05% |
Melting Point |
182-188℃ |
PH (5% solution) |
4.5~6.0 |
UV absorbance(6 molar)@260 |
≤0.03 |
UV absorbance(6 molar)@280 |
≤0.01 |
3.Product Feature And Application
Guanidine Hydrochloride is White Crystal. As intermediate, it is used in many fields. Its Molecular Formula is CH5N3.HCL and its Molecular weight is 95.53. and CAS number is 50-01-1.
Guanidine Hydrochloride can be used to synthesize 2-Aminopyrimidine, 2-amino-6-methylpyrimidine and 2-amino-4,6-dimethylpyrimidine. It is an intermediate for the manufacture of sulfadiazine drugs such as sulfadiazine, sulfamethylpyrimidine and sulfadimethylpyrimidine.
Guanidine hydrochloride reacts with ethyl cyanoacetate to cyclize to 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize anti anemia drug folic acid.
It can also be used as protein denaturant.
As a strong denaturant in the experiment of extracting total RNA from cells. Guanidine hydrochloride solution can dissolve proteins, resulting in the destruction of cell structure and secondary structure of nucleoprotein, which can be dissociated from nucleic acid. In addition, RNase can be inactivated by reducing agents such as guanidine hydrochloride.
So it is used for Corona virus detection.
4.Guanidine Hydrochloride’s production
Taking dicyandiamide and ammonium salt (ammonium chloride) as raw materials, the crude guanidine hydrochloride was obtained by melting reaction at 170-230 ℃, and the finished Guanidine Hydrochloride was refined.
5.Product Qualification
Our factory has passed iso9001:2015 quality system certification, iso14001:2015 environmental management system and iso45001:2018 occupational health and safety management system Thus can ensure the quality and safety of Guanidine Hydrochloride.
6.Package and Deliver
Generally, Guanidine Hydrochloride is with package of 25kg/drum. If you have special requirements, we will customize different packaging types according to your needs.
We can supply Guanidine Hydrochloride in time and shipping by air or by sea. If you have any problems, please feel free to contact us.
7.FAQ
1:Can you produce Guanidine Hydrochloride according to our requirement?
Yes, we can make products according to customer's requirement.
2:Do you provide sample? Free or charge?
Yes, we provide sample. Need sample fee, it is refundable after order confirmation.
3:What is your MOQ?
MOQ 1000g.