Dithiothreitol

1. Product Introduction

Dithiothreitol is mainly used in biomedicine, chemical reagents, etc. Dithiothreitol ( DTT) is mainly used in biochemical research and medicine, Dithiothreitol ( DTT) is as a reducing agent and deprotective agent for SULFHYDRYLATED DNA.
We can produce Dithiothreitol（DTT） with high quality and reasonable price and supply in time, Our customers from Europe, USA, India and we are expecting become your long-term partner in china.

2.Product Technical Parameter

3.Product Feature And Application

Dithiothreitol is white powder, soluble in water, Stability Stable, but heat sensitive. Incompatible with strong oxidizing agents ,its melting point above41 ℃, Keep frozen at -20 to -10 C.Its Molecular Formula is C4H10O2S2 and its Molecular weight is 154.25. and CAS number is 3483-12-3.
Dithiothreitol is easily oxidized by air, the stability of Dithiothreitol (DTT) is poor; However, cryopreservation or treatment in inert gas can prolong its service life. Due to the low nucleophilicity of protonated sulfur, the effective reduction of DTT decreases with the decrease of pH value; Tris (2-carboxyethyl) phosphine HCl (TCEP hydrochloride) can be used as a substitute for DTT at low pH, and it is also more stable than Dithiothreitol (DTT).

Dithiothreitol ( DTT) is mainly used in biochemical research and medicine, Dithiothreitol ( DTT) is as a reducing agent and deprotective agent for Sulfhydrylated DNA. Sulfhydrylated DNA terminal sulfur atoms tend to form dimers in solution, especially in the presence of oxygen. This dimerization greatly reduces the efficiency of some coupling reaction experiments, such as the fixation of DNA in biosensors; Adding Dithiothreitol ( DTT) to DNA solution and removing it after reaction for a period of time can reduce the dimerization of DNA.

Dithiothreitol ( DTT) is also often used to reduce disulfide bonds in proteins, and can be used to prevent intramolecular or intermolecular disulfide bonds formed between cysteines in proteins. However, Dithiothreitol ( DTT) is often unable to reduce the disulfide bonds embedded in the protein structure (inaccessible to the solvent). The reduction of such disulfide bonds often requires protein denaturation (high temperature heating or adding denaturant, such as 6m guanidine hydrochloride, 8m urea or 1% SDS). On the contrary, the depth of embedding can be judged according to the different reduction speed of disulfide bond in the presence of Dithiothreitol ( DTT).

4.Product Qualification

Our factory has passed iso9001:2015 quality system certification, iso14001:2015 environmental management system and iso45001:2018 occupational health and safety management system Thus can ensure the quality and safety of Dithiothreitol ( DTT).

5.Package and Deliver

Generally, Dithiothreitol ( DTT). is with package of 25kg/drum. If you have special requirements, we will customize different packaging types according to your needs. We can supply Dithiothreitol ( DTT). in time and shipping by air or by sea. If you have any problems, please feel free to contact us. It can be Storage at 2-8℃.

6.FAQ

1:Can you produce Dithiothreitol ( DTT) according to our requirement?
Yes, we can make products according to customer's requirement.

2:Do you provide sample? Free or charge?
Yes, we provide sample. Need sample fee, it is refundable after order confirmation.

3:What is your MOQ?
MOQ 1000g.

4:Are there any special requirements for the transportation of Dithiothreitol ( DTT)?
No.