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What are the uses of guanidine hydrochloride (50-01-1)?

2021-09-16

Guanidine hydrochloride, chemical name amidine hydrochloride, molecular formula CH6ClN3, CAS No. 50-01-1, is one of the advantageous products of subfamily technology. Guanidine hydrochloride (50-01-1) is widely used in medicine, pesticide, scientific research and other fields. This paper will introduce the properties, characteristics and main uses of guanidine hydrochloride.


Guanidine hydrochloride is a white crystalline powder with a relative density of 1.354g/ml and a melting point of 180-185 ° C. guanidine hydrochloride is soluble in water, ethanol and methanol, but almost insoluble in acetone, benzene and ether. Guanidine hydrochloride itself is unstable and easy to be hydrolyzed into ammonia and urea. Its toxicity is the same as that of urea, but guanidine and its derivatives are generally more toxic than urea. Guanidine hydrochloride is harmful to inhalation and swallowing and irritating to eyes and skin. Avoid direct contact during operation. Wear protective clothing and goggles for protection.


Guanidine hydrochloride is widely used in many fields. The details are as follows:

 

(1) Intermediate: guanidine hydrochloride is mostly used as the synthetic intermediate of organic compounds such as medicine and pesticide. It is an important raw material for the manufacture of sulfonamides and folic acid;

 

(2) Protein denaturant: guanidine hydrochloride is a commonly used protein denaturant, which is often used for nucleic acid extraction. It can quickly destroy the cell membrane, denature the protein, make the protein denaturate and precipitate, so that the nucleic acid can get rid of the entanglement of the protein;

 

(3) Antibacterial agent: guanidine hydrochloride can be used to prepare guanidine salt antibacterial agent to enhance the antibacterial performance of paper; It can also be used to prepare guanidine based bactericidal scale and corrosion inhibitor, which has broad-spectrum bactericidal performance, can effectively kill sulfuric acid reducing bacteria, saprophytic bacteria and iron bacteria in oilfield water, and remove scaling substances in oilfield reinjection water and scale generated on the inner wall of pipeline;

 

(4) Reducing agent: guanidine hydrochloride can be used as reducing agent to prepare graphene.

 

Guanidine hydrochloride novel coronavirus pneumonia has many other uses. Here is not a summary. It is worth mentioning that guanidine hydrochloride is the raw material for the new crown pneumonia epidemic nucleic acid test reagent, and has important practical value for epidemic prevention and control. In conclusion, guanidine hydrochloride is a very important reagent. Yake technology can stably supply high-quality guanidine hydrochloride products for a long time, with a content of 99% and high cost performance. It can provide products with different specifications from gram level to kilogram level according to customer needs, which can meet the use requirements of different industries.